Oxygen Generators with PSA Technology: Ensuring Reliable Medical Oxygen at the Point of Need

In modern healthcare environments, the availability of medical oxygen is a matter of critical importance. From intensive care units and surgical theaters to emergency departments and rural health centers, oxygen plays a vital role in supporting respiratory function, anesthesia, and life-saving interventions.

Medical Oxygen Concentrator Supply System, manufactured by G. Samaras,
is just one product option among its extensive production line applying the
Pressure Swing Adsorption’’ (PSA) technology, which is a low power consuming solution, efficient and reliable for onsite production of high purity medical oxygen. It uses the basic principle of passing air over adsorbent material which binds with nitrogen to leave a rich stream of oxygen. Our company provides various solutions according to the size and needs of each hospital.

To meet this demand with precision and autonomy, healthcare institutions increasingly rely on Pressure Swing Adsorption (PSA) oxygen generators—on-site technologies that enable continuous, safe, and cost-effective oxygen production.

How PSA Oxygen Generators Work

PSA technology is based on the principle of selective gas separation under pressure. The process includes:

1. Air Compression & Pre-treatment: Ambient air is drawn in and compressed. It is then purified through filters to remove dust, moisture, and oil vapors.

2. Adsorption in Zeolite Beds: The clean, pressurized air is passed into a vessel filled with zeolite molecular sieves, which selectively adsorb nitrogen molecules.

3. Oxygen Output: As nitrogen is retained in the sieve, oxygen (93±3%) flows out as product gas, suitable for medical use.

4. Regeneration Phase: Once the zeolite becomes saturated with nitrogen, the system depressurizes the vessel, releasing the nitrogen into the atmosphere.

5. Twin-Tower Cycling: Two vessels operate in alternating cycles—while one adsorbs nitrogen, the other regenerates—ensuring uninterrupted oxygen production.

Key Technical Features and Benefits of G. Samaras O2 PSA plants

The PSA oxygen generators developed by G. Samaras are designed to meet the rigorous demands of medical application. These systems combine intelligent automation, robust engineering, and modular architecture to ensure consistent performance and reliability.

They enable real-time oxygen generation, reducing the need for gas storage and logistical dependency. With built-in purity sensors and stainless steel components, they operate safely and with high durability—even in space-constrained environments.

Thanks to their modular design, PSA systems can be scaled up as demand increases, while requiring minimal maintenance due to standardized spare parts and simplified servicing. Moreover, their low-pressure operation minimizes safety risks and energy consumption, leading to cost savings of up to 60% compared to conventional supply methods.

On top of that, PSA oxygen generators serve a critical role across the continuum of care when it comes to the clinical applications. In hospitals and clinics, they ensure a steady oxygen supply for intensive care units, surgical departments, and respiratory support. In emergency settings—such as natural disasters or mass casualty incidents—PSA systems provide autonomous operation even in infrastructure-limited environments.

They are also ideal for rural health centers and mobile medical units, where external deliveries may be inconsistent.

Smart Monitoring and Control

To support proactive maintenance and operational transparency, G. Samaras equips its PSA systems with the Medimote remote monitoring platform—developed in-house specifically for medical gas infrastructure.

Medimote offers real-time visualization of system performance, automated alarms, dew point and purity tracking, and secure remote configuration.

Through this platform, biomedical engineers can monitor long-term trends, detect anomalies before they affect performance, and schedule maintenance based on data rather than fixed intervals—optimizing uptime and extending system lifespan.

Smart Automatic Regulating Unit

G. Samaras O2 Generators come with an integrated smart automatic regulating unit for purity stabilization and volume maximization of produced O2, regardless of the external conditions (excessive demand for O2, ambient temperature, pressure/dew point of feeding air etc).

By automatically limiting the long term excessive O2 consumption, this smart regulating unit prevents the collapse of the O2 generator that occurs when the generator operates beyond the limits of allowed working conditions, and simultaneously enables the production of the maximum possible volume of O2, through constant adaptation to the environmental and operational conditions.

When certain abnormal conditions exist that would normally cause the level of purity to drop below a preset minimum acceptable value, the motorized valve automatically steps in, in order to protect the purity, by temporarily limiting the flow. Once the conditions go back to normal, the motorized valve allows the generator to return to its original maximum purity and capacity levels.

O2 Generator Containerized Systems / Mobile Plants

Among its extensive product portfolio, G. SAMARAS is able to provide its clients with oxygen generator containerized systems & mobile O2 Plants. 

Both solutions are turnkey, requiring minimal effort from the client to implement or operate at site, that can be customized as needed, being available in various capacities and oxygen concentrations. Oxygen generators and whole O2 PSA plants in general can be accommodated and preinstalled either inside containers (together with other central stations like medical gases cylinder stations or cylinder filling stations), or skid bases, providing clients with a total plug n’ play solution, operating by just connecting the system with electrical power.

G. SAMARAS containerized and mobile solutions can be easily transported either by road or sea and can be easily placed at site. The O2 generator system can be equipped with greater levels of sound attenuation, different fuel tanks or any other value-added features the client might need.

Certified Safety and Compliance

G. Samaras Medical Oxygen Concentrator Supply System conforms to the following European Standards:

--> EN 286-1

--> EN 60601-1

--> EN ISO 10524-2

--> EN ISO 10524-4

--> EN ISO 14971

--> EN ISO 15001

--> EN ISO 7396-1

--> ISO 10083

Each system undergoes factory testing, performance validation, and quality assurance protocols prior to installation.

Conclusion

Oxygen generators based on PSA technology represent a paradigm shift in how healthcare facilities source and manage their oxygen supply. By delivering high-purity oxygen on-site, they offer unmatched levels of autonomy, safety, and efficiency.

With advanced design, certified quality, and flexible scalability, the PSA solutions developed by G. Samaras are built to support the evolving needs of modern medicine—ensuring that oxygen is always available where and when it’s needed most.